Tofacitinib Intermediate (2R, 3R) -2,3-bis [(4-methylbenzoyl) oxy] succinic acid ati (3R, 4R) - N, 4-dimethyl-1- (phenylmethyl) -3-piperidine amine CAS No.. 477600 -71-8

Awọn agbedemeji tofacitinib wa ṣe pataki ni ilana iṣelọpọ ti tofacitinib, oogun ti a mọ daradara ti a lo lati tọju awọn iru arthritis kan.Agbedemeji yii ṣe ipa pataki ninu iṣelọpọ ti tofacitinib, idasi si imunadoko ati didara rẹ.Nipasẹ (2R, 3R) -2,3-bis [(4-methylbenzoyl) oxy] succinic acid ati (3R,4R) -N,4-dimethyl-1- (phenylmethyl) - Apapo kongẹ ti 3-piperidinamines, wa ọja ṣe idaniloju iṣelọpọ ti tofacitinib to gaju ti o pade ati ju awọn iṣedede ile-iṣẹ lọ.

Ilana molikula ati iwuwo ti agbedemeji tofacitinib wa ṣe afihan mimọ ati agbara rẹ, ti o jẹ ki o jẹ paati igbẹkẹle ti ilana iṣelọpọ oogun.Pẹlu awọn eroja ti o ni iwọn daradara, agbedemeji yii ṣe iṣeduro aitasera ati ipa ti ọja ikẹhin, tofacitinib.Awọn ohun-ini molikula rẹ tun ṣe alabapin si iduroṣinṣin gbogbogbo tofacitinib ati igbesi aye selifu, ni idaniloju pe o wa munadoko ati igbẹkẹle lori igba pipẹ.